Ms Pooja Singh
I am currently working on a project that aims to characterise sequence variation in the xylem transcriptomes of a population of hybrid Eucalyptus trees. This sequence variation in the form of SNPs and indels contributes to the phenotypic diversity observed in quantitative traits such as wood formation. SNPs and indels can have a range of effects on the proteome of the organism. I predict the effects of the variants captured in the transcriptome to assess their impact on transcribed proteins. I am also interested in understanding the interplay between natural selection and deleterious mutations, such as frame-shifting indels and loss-of-function (LoF) variants, as this will enhance our understanding of how genetic variation shapes genomes.
My Journal Articles
|Myburg AA, Grattapaglia D, Tuskan GA, Hellsten U, Hayes RD, Grimwood J, Jenkins J, Lindquist E, Tice H, Bauer D, Goodstein DM, Dubchak I, Poliakov A, Mizrachi E, Kullan ARK, Hussey SG, Pinard D, Van der Merwe K, Singh P, et al. (2014) The genome of Eucalyptus grandis. Nature 510:356-362.