Ms Celiwe Innocentia Nxumalo



PhD student

Department

Biochemistry, Genetics and Microbiology
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Primary Supervisor
Lucy Moleleki

Phytophthora parasitica is one of the most destructive Oomycetes pathogen with a wide host range. During its infection process , P. parasitica secrete RXLR effector proteins as major virulence factor. Recently, a large number of studies have been conducted to elucidate  the biological functions of RXLR effectors from Phytophthora spp. including P. infestans and P. sojae. However, little is known about RXLR effectors from P. parasitica. Therefore, my MSc research aims  to assess the functions of P. parasitica  RXLR effectors in Nicotiana benthamiana immunity.

Understanding the biological functions of P. parasitica  RXLR effectors in N. benthamia immunity could potentially reveal mechanisms underlying Phytopthora pathogenesis and host resistance,which would be beneficial for developing efficient and sustainable disease control strategies for Phytophthora spp. 

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Publication
Jane Chepsergon, Celiwe Nxumalo, Brenda Salasini, Aquillah Kanzi, Lucy Moleleki. (2022) Short Linear Motifs (SLiMs) in “Core” RxLR effectors of Phytophthora parasitica var. nicotianae: A case of PpRxLR1 effector. Microbiology Spectrum 10(2) 10.1128/spectrum.01774-21