A review entitled “Understanding the genetics of sex determination in insects and its relevance to genetic pest management” was recently published by FABI masters student Ms Jade Ashmore and co-authors Prof. Bernard Slippers, Prof. Tuan Duong and Dr Gudrun Dittrich-Schröder in Insect Molecular Biology.

Sex determination in insects controls how males and females develop and offers opportunities for managing pest populations. Insects have different pathways for determining sex, which involve a series of genetic signals and genes. These pathways are complex, varying across species like beetles, flies, wasps, and moths. In many insects, specific genes control the splicing of other genes, which in turn determine sex. Two key genes, Doublesex and Fruitless, regulate physical traits and behaviours linked to being male or female.

By understanding these genetic pathways, scientists can develop methods to manage pests. For example, by targeting female-specific genes, we can create genetic changes that only affect females, either causing them to die or preventing them from reproducing. This leads to a male-heavy population, which reduces the pest population over time. Overall, knowledge of sex determination genetics is crucial for developing effective pest control strategies.

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